Chickasaw is a city in Mobile County, Alabama, United States. As of the 2010 U.S. Census the population is 6,106, a decline from 6,364 in 2000. It is included in the Mobile metropolitan statistical area.
Chickasaw is located at . According to the U.S. Census Bureau, the city has a total area of 4.6 square miles (12 km2), of which, 4.4 square miles (11 km2) of it is land and 0.1 square miles (0.26 km2) of it (3.06%) is water.
Chickasaw's public schools are within the Chickasaw City Schools district. The city voted to form its own school system in 2012.
Chicksaw's public schools were previously operated by the Mobile County Public School System. One elementary school, Hamilton Elementary School, was within the Chickasaw city limits and serves Chickasaw residents. In addition two magnet high schools, Chickasaw School of Mathematics and Science and the Clark School of Mathematics, Science and Technology, were in the city. Residents zoned to Hamilton are also zoned to Chastang Middle School.
Several years prior to 2009 officials of Chickasaw, Satsuma, and Saraland contemplated forming the "Delta School District." Around 2009 Chickasaw officials considered starting a plan to secede from the Mobile County school system after Mobile County officials considered closing the Chickasaw magnets, which together have a combined total of 14% Chickasaw residents; the rest of the students came from other locations, including the unincorporated area of Grand Bay. Mobile County considered moving the magnets to Shaw High School in western Mobile.