Jenkinsville is an incorporated town in western Fairfield County, South Carolina, United States, between the Broad and the Little rivers. It is located east of Monticello Reservoir and is near the Virgil C. Summer Nuclear Generating Station. Also in the area is the Kincaid-Anderson House and quarry. The town is South Carolina's newest, incorporating in 2008. Jenkinsville's population at incorporation was 50, also making it South Carolina's smallest town.
In addition to the Kincaid-Anderson House, the Ebenezer Associate Reformed Presbyterian Church, Dr. John Glenn House, High Point, Little River Baptist Church, and Mayfair are listed on the National Register of Historic Places.