Van Wyck is an unincorporated community in the panhandle of Lancaster County, South Carolina, United States. There are many ways of pronouncing the name of the community- Wick, Wack, and Wike. Families who have lived in this area since its founding in the 1880s generally pronounce it as Van Wyck- as in "there's a lot to like about Van 'Wyck."
Van Wyck is the hometown of Olympian sprint athlete Shawn Crawford, gold and silver medalist from the 2004 games held in Athens, Greece.
The Adam Ivy House and Massey-Doby-Nisbet House were listed on the National Register of Historic Places in 1990.